Troriluzole Trial for Alzheimer's Disease
(T2 Protect AD)
The study is designed to determine if troriluzole can protect against, slow down, and potentially improve memory and thinking problems that increase as Alzheimer’s disease progresses.
More About T2 Protect AD
A potential participant goes through a screening process to determine if he/she is eligible for the T2 Protect clinical trial. Screening includes memory and thinking tests, physical examination, and EKG (heart rhythms).
Participation in the study takes 48 weeks. Study participants visit the study clinic 9 times after enrollment in the trial. At the beginning and end of the study, participants have a brain scan using magnetic resonance imaging (MRI).
Half of study participants are given the active drug and half are given an inactive pill (called a placebo) that looks exactly like the active drug.
T2 Protect AD Basic Eligibility Criteria
Women and men aged 50-85 with mild to moderate Alzheimer’s disease (otherwise, in general good health)
On stable doses of donepezil (Aricept®) or rivastigmine (Exelon®) or galantamine (Razadyne®) for at least 3 months with or without memantine (Namenda®)
Living in the community (not in a residential nursing home)
Having a study partner who has regular contact with the trial participant (about 10 hours per week). The study partner will accompany the participant to the clinic visits
Willing to participate in the T2 Study for 48 weeks
Study-related health monitoring
T2 Protect AD is taking place at more than 30 academic medical centers and clinics specialized in Alzheimer’s disease research, treatment, and care across the United States.
Enter your ZIP code, use the interactive map, or search the listings below to find a location near you.
Not a good fit for T2? Here are additional resources!
There are hundreds of clinical trials recruiting for people with and without Alzheimer’s disease throughout the United States and beyond.
The following resources are available to the people interested in Alzheimer’s clinical research participation:
- In addition to T2, the Alzheimer’s Disease Cooperative Study (ADCS) at the University of California, San Diego has several studies underway across the U.S. Please visit www.adcs.org/clinical-trials.
- The U.S. National Institute of Aging’s Alzheimer’s portal includes a searchable clinical trials database.
You can also call the NIA toll-free at 1-800-438-4380.
- The Alzheimer’s Association’s Trial Match program matches people with research opportunities in their geographic area.
- The Alzheimer’s Prevention Registry provides updates on research and timely clinical trial and study information.
- ClinicalTrials.gov is a resource provided by the U.S. National Library of Medicine. It includes trials taking place throughout the world.